Job offers

Postdoctoral Position Verona Company: University of Verona Department of Department of Neurosciences, Biomedicine and Movement Sciences, Start in 13 February 2017 Duration: one year, with the possibility of renewal.

A postdoctoral research fellow position is immediately available to investigate the role of G-protein coupled receptors in the Alzheimer’s Disease. The project aims at developing new therapeutic approaches that may be translated into clinical applications.

Applicants must have a strong background in live-cell imaging, biochemistry, cell and molecular biology. Whilst a background in Neuroscience is desirable, this is not essential.

Interested candidates should email a cover letter and CV to Prof. Mario Buffelli (mario.buffelli@univr.it). Applications will be considered until the position is filled.

Mario Buffelli, M.D., Ph.D.
Department of Neurosciences, Biomedicine and Movement Sciences,
Section of Physiology and Psychology,
University of Verona,
Strada Le Grazie 8, 37134 Verona, Italy
Email: mario.buffelli@univr.it

Post-doctoral position to study synaptic membrane biology in neurological disease Leuven Company: VIB-KU Leuven Center for Brain & Disease Research Department of Goodchild and Verstreken labs

We have a post-doctoral position to study the cell biological basis of neurological disease in the Goodchild and Verstreken labs in the VIB-KU Leuven Center for Brain & Disease Research in Belgium.

http://cbd.vib.be

Coordinated production of membrane lipids is central to many aspects of neuronal development and function. Furthermore, mutations in lipid metabolic enzymes are connected to many neurological diseases (Grillet, et al, Developmental Cell. 2016; Lauwers, et al, Neuron. 2016) including the related movement disorders of Parkinsons Disease and Dystonia. However, how synapses control the quantity and composition of their membranes is poorly understood. Not least this is because lipid synthesis occurs in the endoplasmic reticulum organelle which is poorly characterized in axons and synapses.

We have a joint post-doc position available in our labs to study how neurological-disease associated defects in lipid metabolism affect organelle and synaptic morphology and function. This project combines neurological disease with classic cell biology and neuroscience, and uses fly as a model organism. Our department houses state of the art live cell imaging capacities, 3D electron microscopy and CLEM, has an electrophysiology core, and CRISPR expertise to generate new genetic models. All these are available for this project.

Your Profile
Publication(s) in neuroscience, cell biology and/ or mechanistic disease research. Helpful to have Drosophila or electrophysiology experience, but priority is given to motivated candidates. The position has funding, although the succesful candidate is also expected to apply for personal fellowships.

About VIB and the VIB-KU Leuven Center for Brain and Disease Research.
VIB is a leading European life science institute, located in Flanders, Belgium. With more than 1470 scientists from over 60 countries, we perform basic research into the molecular foundations of life. The town of Leuven is located in the heart of Europe, with convenient high speed train, motorway and airport transport. In addition, our department is embedded within the KU Leuven university, that is ranked within the world’s top 50, and is a leading academic center.

How to Apply
email to Rose Goodchild (rose.goodchild@kuleuven.vib.be) or Patrik Verstreken (patrik.verstreken@kuleuven.vib.be) with a short personal statement on your interest and a CV.

Post-doctoral position Busto Arsizio Company: University of Insubria Department of Dept. of Biotechnology and Life Sciences Start in 01 October 2017 Duration: 1 year, renewable

A post-doctoral position in Neuroscience is available in the group of Dr. Lia Forti and Prof. Maurizio Popoli, starting October 2017.

Stress increases the risk of psychiatric pathologies, such as anxiety, depression and PTSD. The group has developed a strong interest in a thorough dissection of the brain stress response and search for new druggable targets (Nature Rev Neurosci 2016, 13:22-37; Mol Psychiatry 2014, 19:433–443; Mol Psychiatry 2016, doi: 10.1038/mp.2016.175). Changes in basal glutamatergic transmission and synaptic plasticity have a likely role in the stress response. Our research projects are centred on changes induced by acute stress in glutamatergic evoked and spontaneous synaptic activity and in neuronal morphology in the rodent prefrontal cortex. We aim at distinguishing between vulnerable and resilient individuals and elucidating the molecular and functional basis of differential vulnerability.

Experimental approaches will make extensive use of patch-clamp electrophysiology in acute brain slices from acutely stressed animals. The project design includes behavioural tests, testing of traditional and rapid-acting antidepressants on synaptic function, and morphostructural analysis of neuronal dendrites and spines density.
The project is conducted in close interaction with collaborating neuropsychopharmacology and molecular biology groups: the successful candidate will be exposed to multidisciplinary approaches.

Applicants must have a PhD with a neuroscience background and have experience with in vitro or in vivo brain research. Experience with patch-clamp and brain slice electrophysiology is expected.

Candidates should send a cover letter, curriculum vitae, past research background and accomplishments, copy of degrees, and names of two references to Dr. Lia Forti. The candidate should also state how he/she would imagine his/her role in the project (max 1 page)

Postdoctoral position Milan Company: University of Milan Department of Department of Pharmacological and Biomolecular Sciences Start in 01 October 2017 Duration: Two years

The Laboratory of Neurotoxicology at the Department of Pharmacological and Biomolecular Sciences, University of Milan offers a post-doctoral position within the group leaded by Barbara Viviani.
Our group investigates the molecular mechanisms involved in the modulation of the glutamatergic circuitry by neurotoxicants and neuroinflammation, the relevance in neuronal synaptogenesis and maturation, and the role in an increased neuronal vulnerability to damage.
The successful candidate will be involved in a multi-centre project focusing on micronutrients in early life to preserve the glutamatergic synapse and prevent environmental contaminants induced developmental toxicity. The projects include a combination of in vitro, ex-vivo, biochemical and imaging techniques.
The candidate must have a Ph.D. (or be close to completion) and experience in neuroscience, toxicology and cell biology; be highly motivated, with a strong attitude to independent work and good interpersonal and communication skills (experience in scientific publishing required).
Candidates with prior experience on cell cultures (also primary), animal handling, molecular biology and confocal imaging will have priority. Fluency in English and the ability to work in an international environment is mandatory.
The position is for two years and is expected to start in autumn 2017.
Applications written in English including a cover letter explaining your motivations and previous work, a CV with a list of publications and two reference letters (all assembled is a single PDF document) should be sent to Prof. Barbara Viviani by e-mail (barbara.viviani@unimi.it).

Job requests

Research fellow position Elisabetta Ciani Department of Biomedical and Neuromotor Sciences, University of Bologna - 40126 Bologna 0512091773 elisabetta.ciani@unibo.it